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. 2016 Jan 5;87(6):580–588. doi: 10.1136/jnnp-2015-311945

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Grey matter pathology. (A) Thickness of the right anterior primary motor cortex (BA4a) was reduced in patients with ALS compared to controls (p=0.008); the psALS group did not significantly differ from the other two groups. (B) Focal atrophy of the right caudate nucleus in patients with ALS compared to control participants (structure shown in blue, results for p_FWE<0.05 shown in red). (C) Atrophy of the right caudate nucleus in psALS compared to controls (red, p_FWE=0.074). BA, Brodman Area; _FWE, familywise error.