Figure 2.
Effect of UV-Induced DNA Damage on the CSB and RNAPII Interactomes
(A) Left: UV-induced CSB interactome, in the presence and absence of MG132 as indicated. Right: enlargement of section indicated by box on the left. For clarity, only a few interesting proteins are indicated. Integrator subunits are labeled in yellow.
(B) Western blots of CSB-Flag immunoprecipitation. The CSB-FLAG panel is duplicated to indicate that the panel rows belong to the same experiment. Note that CSB does not seem to enrich a specific, phosphorylated form of RNAPII (left panel).
(C) The RNAPII interactome, in the presence of MG132. Some interesting proteins are indicated. Other proteins can be searched at http://www.biologic-db.org.