Figure 6.

Proteins and Processes that Score Highly in the Multiomic Screening Approach

(A) Bar graph showing the number of proteins that scored above the Z score threshold in one or more screen.

(B) Distribution of hits using aggregated Z scores.

(C) As in (B), but with TC-NER score weighting. In (B) and (C), the colored wheels indicate relative weighting of scores from individual screens (see Figure S1A). Names and dots in red are examples from the TC-NER training category (“TCR”). Please note that, for clarity, even if a candidate scores highly in several scoring schemes, it is typically only indicated once.

(D) Biased list of interesting proteins and protein complexes that scored highly.

(E) Proteins from the TC-NER training category that scored above the Z score threshold (indicated by red bar) in screens across the multiomic approach (see Figure S1B).

See also Figures S2, S3, and S4.