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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Neurobiol Aging. 2016 Mar 26;43:13–22. doi: 10.1016/j.neurobiolaging.2016.03.013

Figure 5.

Figure 5

Normalized thresholds showing percentage deficit of VsEP and 8 kHz ABR dynamic ranges as a function of age. % deficit reflects the loss in sensory dynamic range due to elevated thresholds. 100% indicates complete loss in dynamic range i.e. no response at any stimulus level. Combined male and female data for both strains are represented. A. B6: Percent deficit for VsEP thresholds (open circles) increased slightly with age. The average rate of decline is indicated by the regression line shown (solid): y = 0.50x + 23.2 %. In contrast, ABR percent deficit increased at a steep rate for B6 (dashed line): y = 4.61x + 8.0 %. B. B6.CAST: Percent deficit increased slightly with age similar to B6 at an average rate shown by the regression line shown (solid): y = 0.71 + 18.4 %. Percent deficit for ABR in B6.CAST increased at a significantly higher rate than VsEP but at a significantly lower rate than B6 ABR. Regression line (dashed): y = 3.44 + 3.3 %.