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. Author manuscript; available in PMC: 2016 Jun 23.
Published in final edited form as: Circ J. 2015 Jun 23;79(8):1647–1655. doi: 10.1253/circj.CJ-15-0589

Figure 3.

Figure 3

Natriuretic peptides as novel therapeutic targets in cardiometabolic disease. Adapted from Volpe M, Rubattu S, Burnett J, Jr. Natriuretic peptides in cardiovascular diseases: Current use and perspectives. Eur Heart J. 2014;35:419–425. (Permission pending)

Caption: Natriuretic peptides exert beneficial effects on cardiac and vascular function directly and through inhibition of the renin-angiotensin-aldosterone axis and sympathetic nervous systems, making them ideal and novel targets for cardiovascular protection.