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. 2016 Jun 4;17:72. doi: 10.1186/s12863-016-0384-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — a Representative sequence electropherograms for the c.572G > A (p.(D191G)) mutation for the ENG gene in PAH patients. b Different orthologs for this mutation. c Mutational frequency for this pathogenic mutation in IPAH and APAH patients. 1: Homo sapiens (sp|P17813#1); 2: Homo sapiens mutated (sp|P17813#1); 3: Mus musculus (sp|Q63961#1); 4: Rattus norvegicus (sp|Q6Q3E8#1); 5: Macaca mulatta (sp|F7BB68#1); 6: Sus scrofa (sp|P37176#1); 7: Oryctolagus cuniculus (sp|G1SSF2#1); 8: Canis familiaris (sp|F1P847#1); 9: Bos taurus (sp|Q1RMV1#1); 10: Equus caballus (sp|F6W046#1); 11: Loxodonta africana (sp|G3SR82#1); 12: Ailuropoda melanoleuca (sp|G1M9D6#1)