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. 2016 Jun 4;20:170. doi: 10.1186/s13054-016-1340-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Monocyte toll-like receptor (TLR)2, interleukin-1 receptor-associated kinase (IRAK)3, IRAK4, NLR family pyrin domain containing (NLRP)3, and caspase (CASP)1 mRNA expression of survivors and nonsurvivors after cardiac arrest. Monocyte mRNA expression levels of TLR2 (a), IRAK3 (b), IRAK4 (c), NLRP3 (d), and CASP1 (e) in 30-day survivors (n = 12) and nonsurvivors (n = 11) after 48 h after return of spontaneous circulation (ROSC). The 30-day nonsurvivors had significantly lower monocyte TLR2 (p = 0.003), IRAK3 (p = 0.027), IRAK4 (p = 0.027), NLRP3 (p = 0.006), and CASP1 (p = 0.019) mRNA levels after 48 h after ROSC (p = 0.003). Statistical hypothesis testing was performed using the Mann–Whitney U test. RCN relative copy number