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. Author manuscript; available in PMC: 2016 Jun 4.
Published in final edited form as: Semin Nephrol. 2014 Jun 13;34(4):445–461. doi: 10.1016/j.semnephrol.2014.06.011

Figure 3.

Figure 3

Use of kidney disease iPSCs to investigate molecular pathophysiology. (A) Phase-contrast micrograph showing a colony of undifferentiated iPSCs derived from a patient with ADPKD. Scale bar, 50 µm. (B) Immunolocalization of PC2 and acetylated α-tubulin (AcT) in undifferentiated hPSCs. PC2 localizes to cilia in wild-type ESCs (arrow), but is absent from cilia in ADPKD iPSCs. Scale bar, 10 µm.