Table 2.

Interaction Between Childhood Adversity Interview (CAI) Score and Group (Alcohol-dependent and Control Participants) on BOLD Response during Anticipatory Anxiety

	MNI Coordinates			Volume (voxels)	Z max	Sign of Correlation by Group
region	X	Y	Z			controls	alcohol-dep
lateral OFC, right2	22	24	−18	232	3.54	positive
putamen, right2	34	−2	2	122	3.50		negative
insula, right1	38	0	4	61	3.24		negative
medial OFC, right1	14	22	−20	60	3.39	positive	negative
amygdala, right2	32	−2	−16	111	2.93		negative
medial OFC, left2	−10	30	−20	183	3.48	positive
putamen, left2	−26	−2	2	150	3.56		negative
insula, left2	−36	8	−8	104	3.45		negative

¹corrected p<0.01

²corrected p<0.0001