Table 5.
Regression results for histopathological markers and genotype (N = 62)
| Histopathological marker |
Covariate | Standardized beta value |
p-value (for covariate) |
|---|---|---|---|
| HLA-DR | Age at death | −.198 | .168 |
| Education | −.172 | .243 | |
| Race | −.136 | .351 | |
| Nadir CD4 cell count | .074 | .614 | |
| Log10 blood HIV viral load | .018 | .905 | |
| Duration of HIV infection | −.054 | .709 | |
| F value overall fit (p-value) | .564 (.757) | ||
| Adjusted R squared | −.045 | ||
| Iba1 | Age at death | −.152 | .245 |
| Education | .044 | .741 | |
| Race | −.086 | .514 | |
| Nadir CD4 cell count | −.145 | .296 | |
| Log10 blood HIV RNA viral load | .292 | .030 | |
| Duration of HIV infection | −.042 | .750 | |
| MIP-1α genotype | −.379 | .005 | |
| DRD3 genotype | .271 | .036 | |
| F value overall fit (p-value) | 2.813 (.01) | ||
| Adjusted R squared | .192 | ||
| GFAP | Age at death | .065 | .577 |
| Education | .211 | .083 | |
| Race | .106 | .385 | |
| Nadir CD4 cell count | .002 | .985 | |
| Log10 blood HIV RNA viral load | −.005 | .967 | |
| Duration of HIV infection | .333 | .007 | |
| IL1α genotype | .444 | .0002 | |
| F value overall fit (p-value) | 4.787 (.0003) | ||
| Adjusted R squared | .303 | ||
| A-Beta | Age at death | .260 | .052 |
| Education | .076 | .575 | |
| Race | .148 | .267 | |
| Nadir CD4 cell count | .112 | .401 | |
| Log10 blood HIV RNA viral load | −.143 | .296 | |
| Duration of HIV infection | −.012 | .927 | |
| ApoE genotype | .245 | .048 | |
| F value overall fit (p-value) | 2.474 (.028) | ||
| Adjusted R squared | .145 |