Table 1.
N | Luminal A (HER2−) | P‐valuea | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
ER+/PR+ | ER+/PR− | ER−/PR+ | ER+/PR+: | ER+/PR+: | ER+/PR−: | |||||
N | % | N | % | N | % | ER+/PR− | ER−/PR+ | ER−/PR+ | ||
Total | 118,285 | 102,087 | 14,994 | 1204 | ||||||
Age at diagnosis | <0.0001 | <0.0001 | <0.0001 | |||||||
<50 | 21,777 | 19,299 | 18.9 | 2081 | 13.9 | 397 | 33.0 | |||
50–64 | 43,550 | 37,261 | 36.5 | 5849 | 39.0 | 440 | 36.5 | |||
65–74 | 28,705 | 24,836 | 24.3 | 3670 | 24.5 | 199 | 16.5 | |||
≥75 | 24,253 | 20,691 | 20.3 | 3394 | 22.6 | 168 | 14.0 | |||
Race/ethnicity | <0.0001 | <0.0001 | <0.0001 | |||||||
NH white | 85,717 | 74,701 | 73.2 | 10,297 | 68.7 | 719 | 59.7 | |||
NH black | 10,540 | 8371 | 8.2 | 1930 | 12.9 | 239 | 19.9 | |||
Asian/Pacific Islander | 9117 | 7956 | 7.8 | 1094 | 7.3 | 67 | 5.6 | |||
Am.Indian/AlaskaNative | 633 | 555 | 0.5 | 71 | 0.5 | 7 | 0.6 | |||
Hispanic | 11,429 | 9766 | 9.6 | 1496 | 10.0 | 167 | 13.9 | |||
Unknown | 849 | 738 | 0.7 | 106 | 0.7 | 5 | 0.4 | |||
AJCC stage | <0.0001 | <0.0001 | <0.0001 | |||||||
0–I | 64,491 | 57,029 | 55.9 | 7018 | 46.8 | 444 | 36.9 | |||
II | 34,905 | 29,601 | 29.0 | 4809 | 32.1 | 495 | 41.1 | |||
III | 11,352 | 9329 | 9.1 | 1868 | 12.5 | 155 | 12.9 | |||
IV | 4979 | 3997 | 3.9 | 900 | 6.0 | 82 | 6.8 | |||
Unknown | 2558 | 2131 | 2.1 | 399 | 2.7 | 28 | 2.3 | |||
Tumor size | 0.1503 | <0.0001 | <0.0001 | |||||||
≤0.5 cm | 10,091 | 8724 | 8.5 | 1316 | 8.8 | 51 | 4.2 | |||
>0.5 cm | 104,379 | 90,257 | 88.4 | 13,021 | 86.8 | 1101 | 91.4 | |||
Unknown | 3815 | 3106 | 3.0 | 657 | 4.4 | 52 | 4.3 | |||
Poverty index | 0.0833 | <0.0001 | <0.0001 | |||||||
Q1 | 28,333 | 24,551 | 24.0 | 3516 | 23.4 | 266 | 22.1 | |||
Q2 | 27,526 | 23,778 | 23.3 | 3513 | 23.4 | 235 | 19.5 | |||
Q3 | 28,566 | 24,569 | 24.1 | 3736 | 24.9 | 261 | 21.7 | |||
Q4 | 33,837 | 29,170 | 28.6 | 4226 | 28.2 | 441 | 36.6 | |||
Unknown | 23 | 19 | 0.0 | 3 | 0.0 | 1 | 0.1 |
Summary of clinical and demographic characteristics of hormone receptor‐positive (HR+), HER2− Luminal A breast cancers in women with invasive breast cancer: Surveillance, Epidemiology and End Results 18, 2010–2012. NH, non‐Hispanic; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor 2.
P‐value calculations do not include unknown values.