Table 4.
Factor | n |
Univariate analysis |
Multivariate analysis |
||||
3-yr CSS | 5-yr CSS | P value | HR(95%CI) | P value | |||
Gender | M | 141 | 88.3% | 80.8% | 0.924 | ||
F | 93 | 87.8% | 79.7% | ||||
Age (yr) | ≥ 75 | 96 | 82.2% | 71.6% | 0.027 | 1.464 (0.647-3.310) | 0.360 |
< 75 | 138 | 91.9% | 85.4% | ||||
ASA-PS | 1 | 71 | 86.0% | 83.5% | 0.710 | ||
2-3 | 163 | 89.0% | 78.7% | ||||
BMI (kg/m2) | ≥ 25 | 28 | 92.0% | 85.8% | 0.389 | ||
< 25 | 193 | 87.3% | 80.0% | ||||
Serum albumin (g/dL) | ≤ 4.0 | 172 | 85.6% | 82.6% | 0.536 | ||
> 4.0 | 48 | 87.7% | 76.2% | ||||
CEA (mg/dL) | ≥ 5.0 | 102 | 86.7% | 80.0% | 0.715 | ||
< 5.0 | 113 | 90.5% | 82.0% | ||||
Decompression | + | 183 | 88.4% | 81.7% | 0.514 | ||
- | 51 | 87.1% | 74.8% | ||||
Location of tumor | Right side | 69 | 82.6% | 70.5% | 0.103 | ||
Left side | 165 | 90.4% | 84.3% | ||||
Tumor size (mm) | ≥ 50 | 99 | 84.1% | 76.9% | 0.291 | ||
< 50 | 121 | 90.4% | 85% | ||||
Differentiation of tumor | tub1, tub2 | 222 | 89.9% | 82.5% | 0.001 | 6.282 (1.584-24.909) | 0.009 |
por, muc | 12 | 50.0% | 50.0% | ||||
Depth of tumor | T3 | 108 | 95.7% | 92.3% | 0.001 | 3.458 (1.324-9.031) | 0.011 |
T4 | 126 | 81.1% | 69.2% | ||||
Intramural lymphatic invasion | + | 157 | 90.8% | 82.7% | 0.449 | ||
- | 73 | 86.9% | 79.4% | ||||
Intramural vascular invasion | + | 164 | 94.2% | 90.1% | 0.152 | ||
- | 70 | 85.9% | 76.7% | ||||
Lymph node involvement | + | 120 | 92.5% | 82.9% | 0.332 | ||
- | 114 | 84.0% | 77.7% | ||||
Lymph node dissection | D0, D1 | 31 | 60.7% | 60.7% | 0.014 | 0.958 (0.300-3.056) | 0.942 |
D2, D3 | 199 | 90.4% | 83.0% | ||||
No. of lymph nodes harvested | < 12 | 73 | 83.3% | 78.3% | 0.314 | ||
≥ 12 | 151 | 91.1% | 81.0% | ||||
Postoperative complication | + | 78 | 85.9% | 75.6% | 0.644 | ||
(≥ Grade 2) | - | 156 | 89% | 82.5% | |||
Anastomotic leakage | + | 18 | 100% | 100% | 0.069 | ||
- | 191 | 87.1% | 78.7% | ||||
Curability | R0 | 219 | 91.3% | 84.7% | < 0.001 | 6.162 (1.692-22.445) | 0.006 |
R1 | 15 | 39.7% | 19.9% | ||||
Adjuvant chemotherapy | + | 91 | 87.7% | 81.8% | 0.800 | ||
- | 143 | 88.8% | 79.4% |