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. 2016 Jun 6;10:240. doi: 10.3389/fnins.2016.00240

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Copyright © 2016 Zamroziewicz and Barbey.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of aging on brain structure (cortical thickness) in healthy older adults (mean age 63.38 ± 12.23 years). Regions highlighted in green follow a linear rate of atrophy. Regions highlighted in orange show decline early in aging, stabilize, and then decline again late in aging. Regions highlighted in red show decline early in aging (decrease quickly early in aging but stabilize late in aging). Regions highlighted in yellow show decline late in aging (remain structurally intact early in aging but decrease quickly late in aging). Modified from Claassen et al. (2016) in Aging and Disease licensed under CC BY.