Table 6. Studies reporting intermediate and long term outcomes.
| Author, year | Institution | Survival (HA vs. TA)** | Freedom from aortic reoperation (HA vs. TA)** | Mortality from aortic reoperation (HA vs. TA) |
|---|---|---|---|---|
| Shi et al., 2014 | Shenyang, China | 88.3% for whole cohort at 5 years, P=0.56 | 88% vs. 91.3% at 5 years, P=0.62; pooled HR =0.98 (95% CI: 0.30–3.23) | No death in either groups |
| Ohtsubo et al., 2002 | Saga, Japan | 91.3%±5.9% vs. 44.4%±14.3% at 5 years, P=0.018 | 93.8%±6.3% vs. 100%±0% at 5 years, P=0.86; HR = NA | NS |
| Tan et al., 2003 | Nieuwegein, Netherlands | 66% and 40% at 5 and 10 years for whole cohort, P=0.84 | 96.3% and 77.0% at 5 and 10 years for whole cohort, P=0.21; pooled HR =1.05 (95% CI: 0.18–6.15) | No death in either groups |
| Uchida et al., 2009 | Hiroshima, Japan | 69% vs. 95.3% at 5 years, P=0.03 | 70.3% vs. 88.6% at 5 years, P=0.02; pooled HR =0.31 (95% CI: 0.10–0.94) | None reported |
| Rylski et al., 2014 | Freiburg, Germany | 64% vs. 79% at 5 years, P=0.0062 | 97%±3% vs. 100% at 5 years, P=0.440; pooled HR =0.25 (95% CI: 0.00–25.30) | 1 died in the hemiarch group |
| Kim et al., 2010 | Seoul, South Korea | 83.2%±3.3% vs. 65.8±8.3% at 5 years, P=0.013 | 92.8%±2.8% vs. 88.0%±8.5% at 5 years, P=0.87; pooled HR =1.71 (95% CI: 0.39–7.46) | No death in either groups |
| Shiono et al., 2006 | Tokyo, Japan | 63.5% vs. 80.8% at 10 years, P=0.72 | 60.9% vs. 76.6% at 10 years, P=0.48; pooled HR =0.78 (95% CI: 0.19–3.13) | No death reported in either groups |
| Zhang et al., 2014 | Shanghai, China | 80.5% vs. 87.7% at 8 years, P=0.11 | NS | 1 died in hemiarch group |
| Sun et al., 2014 | Beijing, China | No significant differences, P=0.943 | NS | No death reported in either groups |
| Di Eusanio et al., 2015 | Bologna, Italy | 57.2%±4.2% vs. 52.1%±9.9% at 7 years, P=0.89 | 85.4%±3.9% vs. 71.6%±13.2% at 7 years, P=0.29; pooled HR =1.56 (95% CI: 0.53–4.58) | No death reported in either groups |
| Rice et al., 2015 | Texas, USA | 61.3% vs. 61.2% at 10 years, P=0.209 | NS | NS |
| Omura et al., 2016 | Kobe, Japan | 76.5%±5.8% vs. 81.8%±7.6% at 10 years, P=0.54 | 83.3%±5.3% vs. 91.7%±4.6% at 10 years, P=0.20; pooled HR =0.32 (95% CI: 0.10–1.01) | No death in either groups |
| Vallabhajosyula et al., 2015 | Philadelphia, USA | 73%±8.3% vs. 67%±8.6% at 5 years, P=0.56 | NS | No death in either groups |
| Dai et al., 2015 | Fujian, China | 83.3% vs. 94.1% at 5 years, P<0.05 | NS | 1 died in hemiarch group due to descending aortic dilatation |
| Overall pooled HR (95% CI) | NA | NA | 0.73 (95% CI: 0.46–1.18); P=0.20; I2=13% | NA |
**, actuarial survival data and freedom from aortic reoperation were prepared using Kaplan-Meier cumulative survival method. Data were compared using the log-rank test. NS, not specified; HR, hazard ratio; CI, confidence interval; HA, hemiarch; TA, total arch.