Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 May 25;5(5):e51. doi: 10.1038/emi.2016.51

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016 Shanghai Shangyixun Cultural Communication Co., Ltd

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Expression constructs and homology remodeling of chimeric protrusion (P) particles. (A) Predicted loops of the HA2:90-105 region in NoV P particles are shown with the epitope fully exposed on the surface of the P particles. (B) The sequence DIWTYNAELLVLLENE from HA2 of the H1 virus (red) was inserted between the G274 and T275 residues in loop 1 of the NoV P domain via a GGGS linker. The sequence DLWSYNAELLVALENQ from HA2 of the H3 virus (yellow) was inserted between the S372 and N373 residues in loop 2 via a GGGS linker. The sequence DTISSQIELAVLLSNE from HA2 of the B virus (blue) was inserted between the G392 and S393 residues in loop 3 via a GGGS linker.