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. 2016 May 23;2016:2174682. doi: 10.1155/2016/2174682

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Copyright © 2016 Hong Lu et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Matrix deposition and MIF expression were enhanced in IRI kidneys. (a) HE and Masson staining revealed marked inflammatory cell infiltration and interstitial injury in IRI kidneys tissues of BUO rats. Bar: 50 μm. (b) Gene expression of type III collagen in IRI kidneys was upregulated. (c) IRI induced the upregulation of TGF-β1 levels in IRI kidneys. (d) IRI induced upregulated expression of MIF in IRI kidneys. (e) Increased expression of MIF and CD68 in kidneys of IRI rats. Bar: 50 μm.