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. 2016 Jun 6;6:27149. doi: 10.1038/srep27149

Figure 1. IL-17A expression in human tendinopathy samples.

Figure 1

(A) Graphs illustrate modified Bonar scoring for samples of human tendon biopsies for expression of CD3, CD68 and MCT markers with mean and SEM shown. n = 10 for control tendon, n = 10 for torn tendon and early tendinopathy. Modified Bonar scoring system depicts mean score per sample based on 10 high power fields. 0 = no staining, 1 = <10%, 2 = 10–20%, 3 = >20% + ve staining of cells per high power field. *p < 0.05, **p < 0.01 (Students t-test) (B) IL-17A gene expression in tendon samples. Delta Ct values of IL-17A in control (n = 10, intact subscapularis biopsy), torn tendon (torn supraspinatus biopsy) and early tendinopathy (matched intact subscapularis biopsy) human tendon samples (n = 10). Data are mean ± SD relative to house keeping gene18S (mean of duplicate analysis). *p < 0.05, **p < 0.01 (Students t-test). (C) Quantitative expression of CD3 + /IL-17+, CD68 + /IL17+ and MCT/IL-17+ depicts mean cells per sample based on 10 high power fields. n = 10 for control tendon, n = 10 for torn tendon and early tendinopathy *p < 0.05, **p < 0.01 versus control tissue, (Students t-test).