Table 3. Antiproliferative activities of VLX1570, b-AP15 and bortezomib on multiple myeloma cells.

Compound	VLX1570	b-AP15	bortezomib
KMS-11	43 ± 2	83 ± 3	67 ± 3
RPMI8226	74 ± 2	150 ± 14	84 ± 5
OPM-2	126 ± 3	160 ± 3	32 ± 1
OPM-2-BZR	191 ± 1	268 ± 12	204 ± 10

Shown in this table are IC₅₀ values in nanomolar (nM) determined over 72 hours using the MTT assay.