Table 3. Summary the results of the total and subgroup analyses in different genetic models.
Variables | AA + AG vs. GG |
AA vs. AG + GG |
AA vs. GG |
AG vs. GG |
A vs. G |
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | OR | 95% CI | P | |
Total | 1.33 | 1.17–1.51 | <0.001 | 1.28 | 1.11–1.47 | 0.001 | 1.43 | 1.24–1.65 | <0.001 | 1.35 | 1.19–1.54 | <0.001 | 1.26 | 1.14–1.40 | <0.001 |
Ethnicities | |||||||||||||||
Caucasian | 1.07 | 0.98–1.16 | 0.15 | 1.03 | 0.82–1.29 | 0.81 | 1.07 | 0.85–1.35 | 0.55 | 1.10 | 1.00–1.21 | 0.05 | 1.07 | 1.00–1.15 | 0.06 |
Asian | 1.63 | 1.34–1.98 | <0.001 | 1.42 | 1.05–1.93 | 0.02 | 1.71 | 1.28–2.30 | <0.001 | 1.58 | 1.28–1.95 | <0.001 | 1.45 | 1.25–1.68 | <0.001 |
Mixed | 1.21 | 0.87–1.69 | 0.26 | 0.92 | 0.25–3.34 | 0.90 | 0.82 | 0.37–1.81 | 0.62 | 1.28 | 0.90–1.82 | 0.16 | 1.11 | 0.83–1.47 | 0.48 |
Types | |||||||||||||||
Breast cancer | 1.26 | 1.11–1.44 | <0.001 | 1.21 | 0.93–1.59 | 0.16 | 1.36 | 1.03–1.79 | 0.03 | 1.26 | 1.10–1.44 | <0.001 | 1.20 | 1.08–1.33 | <0.001 |
Gynaecological cancer | 0.98 | 0.83–1.16 | 0.81 | 1.36 | 0.93–1.99 | 0.12 | 1.36 | 0.92–2.01 | 0.13 | 0.94 | 0.79–1.12 | 0.52 | 1.03 | 0.89–1.18 | 0.71 |
Urologic cancer | 1.56 | 1.32–1.85 | <0.001 | 1.34 | 0.75–2.38 | 0.32 | 1.62 | 0.97–2.69 | 0.06 | 1.46 | 1.10–1.93 | <0.001 | 1.31 | 1.09–1.57 | <0.001 |
Digestive system cancer | 1.25 | 0.79–1.98 | 0.34 | 0.83 | 0.55–1.27 | 0.40 | 0.88 | 0.57–1.35 | 0.55 | 1.38 | 0.82–2.33 | 0.23 | 1.26 | 0.80–1.97 | 0.32 |
Hematologic malignancy | 1.17 | 0.97–1.41 | 0.09 | 0.95 | 0.57–1.59 | 0.98 | 1.06 | 0.63–1.78 | 0.83 | 1.29 | 1.04–1.59 | 0.02 | 1.18 | 0.99–1.40 | 0.07 |
Lung cancer | 1.80 | 1.36–2.39 | <0.001 | 2.24 | 1.41–3.57 | <0.001 | 2.86 | 1.75–4.69 | <0.001 | 1.62 | 1.20–2.18 | <0.001 | 1.65 | 1.34–2.04 | <0.001 |
Head and neck cancer | 1.3 | 0.68–2.48 | 0.43 | 0.76 | 0.40–1.46 | 0.41 | 0.92 | 0.47–1.80 | 0.81 | 1.35 | 0.70–1.61 | 0.37 | 1.16 | 0.71–1.91 | 0.55 |
OR = odds ratio; CI = confidence interval.