Table 5.

Logistic models for pain persistence based on smoking, additional behavioral parameters and for mediation effect by brain NAc‐mPFC functional connectivity

Parameter	OR (s.e.m.)	P	95% CI
Model 1, smoking alone
Smoking	3.17 (1.79)	0.04	[1.05, 9.57]
N = 68; AUC = 0.62; LR χ2 = 4.53, P = 0.03
Model 2, smoking + NAc‐mPFC
Smoking	1.56 (0.95)	0.463	[0.48, 5.14]
NAc‐mPFCa	1.85 (0.37)	0.002	[1.25, 2.74]
Preliminary multiparameter model
Smoking	5.86 (4.78)	0.030	[1.18, 29.01]
MPQa	1.54 (0.34)	0.052	[1.00, 2.37]
painDETECT	1.15 (0.11)	0.137	[0.96, 1.39]
MQS	0.72 (0.11)	0.028	[0.54, 0.97]
N = 53; AUC = 0.89; LR χ2 = 27.8, P < 10−4
Final multiparameter model
Smoking	4.79 (3.21)	0.019	[1.29, 17.8]
MPQa	1.48 (0.19)	0.002	[1.15, 1.92]
MQS	0.771 (0.09)	0.018	[0.62, 0.96]
N = 68; AUC = 0.82; LR χ2 = 25.3, P < 10−4
Final model + NAc‐mPFC
NAc‐mPFCa	1.63 (0.35)	0.021	[1.08, 2.48]
Smoking	2.96 (2.20)	0.144	[0.69, 12.70]
MPQa	1.39 (0.19)	0.013	[1.07, 1.81]
MQS	0.737 (0.10)	0.019	[0.57, 0.95]
N = 68; AUC = 0.86; LR χ2 = 31.8, P < 10−4

^aOdds Ratio represent a 0.1 increment in correlation between NAc‐mPFC, range: [−0.23,0.66].