Forest plot of multivariable adjusted hazard ratios for the risk of thromboembolism or death according to features of cardiac structure and function among subjects with atrial fibrillation in the ENGAGE AF-TIMI 48 echocardiography sub-study.
Multivariable adjusted hazard ratios (point) and 95%CI (line) from Cox proportional hazards models. Covariates included CHADS2 score, aspirin use at baseline, randomization to warfarin, edoxaban (low dose), edoxaban (high dose), and all of the features of cardiac structure and function shown. Hazard ratios reflect risk per 1 standard deviation increase. LA diam = left atrial diameter. Other abbreviations as in Table 2.