Table 2.

Traditional lipid profile, lipoprotein particle size and concentration, and vascular smooth muscle biomarkers in metabolically healthy obese PCOS (MHO-PCOS) girls and metabolically unhealthy obese (MUHO-PCOS) girls in the total cohort.

Variables	MHO-PCOS (n=19)	MUHO-PCOS (n=51)	P	Adjusted* P
Traditional Lipid Profile
Total cholesterol (mg/dL)	143.4 ± 6.6	160.2 ± 4.7	0.055	NS
Triglyceride (mg/dL)	114.5 ± 14.1	126.1 ± 8.3	NS	NS
HDL (mg/dL)	41.1 ± 2.7	40.4 ± 1.2	NS	NS
LDL (mg/dL)	79.4 ± 5.2	94.6 ± 4.2	NS	NS
VLDL (mg/dL)	22.4 ± 2.7	24.9 ± 1.6	NS	NS
Non-HDL cholesterol (mg/dL)	98.4 ± 11.9	121.7 ± 4.8	0.035	0.077
Lipoprotein Particle Size
HDL particle size (nm)	8.9 ± 0.3	8.7 ± 0.3	0.026	0.046†
LDL particle size (nm)	21.2 ± 0.8	20.7 ± 0.7	0.065	NS
VLDL particle size (nm)	50.5 ± 2.7	54.1 ± 1.8	NS	NS
Lipoprotein Particle Concentration
Large VLDL (nmol/L)	2.5 ± 1.1	3.8 ± 0.6	0.027	0.006#†
Medium VLDL (nmol/L)	17.9 ± 4.1	19.5 ± 1.9	NS	NS
Small VLDL (nmol/L)	21.9 ± 3.3	31.1 ± 2.3	0.039	NS
IDL (nmol/L)	21.4 ± 8.8	41.5 ± 6.2	0.021	NS
Large LDL (nmol/L)	286.3 ± 48.3	260.8 ± 22.8	NS	NS
Medium-small LDL (nmol/L)	93.6 ± 17.9	135.4 ± 11.1	0.055	NS
Very small LDL (nmol/L)	332.0 ± 54.1	520.1 ± 48.1	0.035	0.096
Large HDL (mmol/L)	4.9 ± 0.7	4.5 ± 0.5	NS	NS
Medium HDL (mmol/L)	4.1 ± 0.6	4.2 ± 0.5	NS	NS
Small HDL (mmol/L)	13.4 ± 1.0	16.7 ± 0.7	0.021	0.065
Vascular Smooth Muscle Biomarkers
ICAM-1 (ng/mL)	172.2 ± 14.6	219.1 ± 17.3	NS	NS
VCAM-1 (ng/mL)	550.0 ± 75.8	615.2 ± 47.0	NS	NS
E-selectin (ng/mL)	37.5 ± 4.6	127.6 ± 45.5	NS	NS

Values are mean ± SEM.

^*P adjusted for race and Tanner stage.

^#indicates P <0.01 after adjusting for BMI in addition to race and Tanner stage.

^†indicates P <0.01 after adjusting for glucose tolerance status in addition to race and Tanner stage.

NS, not-significant.