Table 6.
Comparison of UV and MS results for silymarin extracts. Percent composition of compounds 1–8 in various commercial silymarin extracts.
| Extract | Total† | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Madaus | UV | 67 | 2.71 (0.01) | 1.89 (0.02) | 8.63 (0.14) | 11.00 (0.03) | 13.91 (0.02) | 19.49 (0.08) | 5.48 (0.02) | 3.46 (0.02) |
| 37501 | MS | 70 | 2.65 (0.04) | 1.95 (0.05) | 8.79 (0.07) | 14.18 (0.10) | 13.85 (0.15) | 19.38 (0.36) | 5.58 (0.05) | 3.53 (0.07) |
| Madaus | UV | 63 | 2.84 (0.04) | 0.54 (0.01) | 13.40 (0.09) | 1.43 (0.02) | 15.29 (0.05) | 22.62 (0.13) | 4.56 (0.03) | 1.97 (0.02) |
| 286061 | MS | 62 | 2.81 (0.08) | 0.52 (0.04) | 13.33 (0.09) | 1.44 (0.09) | 15.17 (0.20) | ALR | 4.64 (0.07) | 1.94 (0.03) |
| Indena | UV | 56 | 4.13 (0.02) | 1.30 (0.01) | 11.53 (0.06) | 5.48 (0.04) | 10.16 (0.02) | 15.94 (0.11) | 4.917 (0.001) | 2.50 (0.02) |
| 27691 | MS | 57 | 4.13 (0.05) | 1.22 (0.05) | 11.60 (0.05) | 7.02 (0.01) | 10.29 (0.11) | 15.68 (0.04) | 4.92 (0.14) | 2.52 (0.01) |
| Sigma | UV | 46 | 3.17 (0.01) | 0.84 (0.01) | 10.15 (0.05) | 3.27 (0.04) | 9.17 (0.04) | 13.60 (0.04) | 3.84 (0.01) | 1.97 (0.04) |
| BCBJ0393V | MS | 47 | 3.00 (0.08) | 0.89 (0.06) | 10.25 (0.05) | 4.05 (0.07) | 9.20 (0.07) | 13.93 (0.20) | 3.87 (0.07) | 1.99 (0.09) |
| Sigma | UV | 54 | 2.60 (0.03) | 0.437 (0.003) | 13.14 (0.05) | 0.83 (0.02) | 12.50 (0.03) | 18.42 (0.06) | 4.20 (0.01) | 1.62 (0.01) |
| 05503PG | MS | 54 | 2.61 (0.01) | 0.40 (0.02) | 13.08 (0.05) | 0.82 (0.05) | 12.51 (0.06) | 18.49 (0.24) | 4.22 (0.08) | 1.70 (0.04) |
†
Total percentage of the silymarin extract contributed by the eight compounds being measured in this study
Shaded values for percent composition indicate a statistically significant difference (at the 95% confidence interval) between the percent composition measured by MS versus UV detection according to the t-test. Unshaded values showed no statistically significant difference between MS and UV data.
ALR = above linear range of the MS detection method
BQL = below quantitation limit
ND = not detected