Table 1. Genes on the Human Fibrosis RT2 PCR Array (Qiagen).
| Symbol | Description | Gname |
|---|---|---|
| ACTA2 | Actin, alpha 2, smooth muscle, aorta | AAT6/ACTSA |
| AGT | Angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | ANHU/FLJ92595/FLJ97926/SERPINA8 |
| AKT1 | V-akt murine thymoma viral oncogene homolog 1 | AKT/MGC99656/PKB/PKB-ALPHA/PRKBA/RAC/RAC-ALPHA |
| BCL2 | B-cell CLL/lymphoma 2 | Bcl-2 |
| BMP7 | Bone morphogenetic protein 7 | OP-1 |
| CAV1 | Caveolin 1, caveolae protein, 22kDa | BSCL3/CGL3/MSTP085/VIP21 |
| CCL11 | Chemokine (C-C motif) ligand 11 | MGC22554/SCYA11 |
| CCL2 | Chemokine (C-C motif) ligand 2 | GDCF-2/HC11/HSMCR30/MCAF/MCP-1/MCP1/MGC9434/SCYA2/SMC-CF |
| CCL3 | Chemokine (C-C motif) ligand 3 | G0S19-1/LD78ALPHA/MIP-1-alpha/MIP1A/SCYA3 |
| CCR2 | Chemokine (C-C motif) receptor 2 | CC-CKR-2/CCR2A/CCR2B/CD192/CKR2/CKR2A/CKR2B/CMKB R2/FLJ78302/MCP-1-R/MGC103828/MGC111760/MGC168006 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | C/EBP-beta/CRP2/IL6DBP/LAP/MGC32080/NF-IL6/TCF5 |
| COL1A2 | Collagen, type I, alpha 2 | OI4 |
| COL3A1 | Collagen, type III, alpha 1 | EDS4A/FLJ34534 |
| CTGF | Connective tissue growth factor | CCN2/HCS24/IGFBP8/MGC102839/NOV2 |
| CXCR4 | Chemokine (C-X-C motif) receptor 4 | CD184/D2S201E/FB22/HM89/HSY3RR/LAP3/LCR1/LE STR/NPY3R/NPYR/NPYRL/NPYY3R/WHIM |
| DCN | Decorin | CSCD/DSPG2/PG40/PGII/PGS2/SLRR1B |
| EDN1 | Endothelin 1 | ET1/HDLCQ7/PPET1 |
| EGF | Epidermal growth factor | HOMG4/URG |
| ENG | Endoglin | CD105/END/FLJ41744/HHT1/ORW/ORW1 |
| FASLG | Fas ligand (TNF superfamily, member 6) | APT1LG1/CD178/CD95-L/CD95L/FASL/TNFSF6 |
| GREM1 | Gremlin 1 | CKTSF1B1/DAND2/DRM/GREMLIN/IHG-2/MGC126660 |
| HGF | Hepatocyte growth factor (hepapoietin A; scatter factor) | DFNB39/F-TCF/HGFB/HPTA/SF |
| IFNG | Interferon, gamma | IFG/IFI |
| IL10 | Interleukin 10 | CSIF/IL-10/IL10A/MGC126450/MGC126451/TGIF |
| IL13 | Interleukin 13 | ALRH/BHR1/IL-13/MGC116786/MGC116788/MGC116789/P600 |
| IL13RA2 | Interleukin 13 receptor, alpha 2 | CD213A2/CT19/IL-13R/IL13BP |
| IL1A | Interleukin 1, alpha | IL-1A/IL1/IL1-ALPHA/IL1F1 |
| IL1B | Interleukin 1, beta | IL-1/IL1-BETA/IL1F2 |
| IL4 | Interleukin 4 | BCGF-1/BCGF1/BSF-1/BSF1/IL-4/MGC79402 |
| IL5 | Interleukin 5 (colony-stimulating factor, eosinophil) | EDF/IL-5/TRF |
| ILK | Integrin-linked kinase | DKFZp686F1765/ILK-2/P59 |
| INHBE | inhibin, beta E | MGC4638 |
| ITGA1 | Integrin, alpha 1 | CD49a/VLA1 |
| ITGA2 | Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | BR/CD49B/GPIa/VLA-2/VLAA2 |
| ITGA3 | Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | CD49C/FLJ34631/FLJ34704/GAP-B3/GAPB3/MSK18/VCA-2/VL3A/VLA3a |
| ITGAV | Integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | CD51/DKFZp686A08142/MSK8/VNRA |
| ITGB1 | Integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | CD29/FNRB/GPIIA/MDF2/MSK12/VLA-BETA/VLAB |
| ITGB3 | Integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | CD61/GP3A/GPIIIa |
| ITGB5 | Integrin, beta 5 | FLJ26658 |
| ITGB6 | Integrin, beta 6 | - |
| ITGB8 | Integrin, beta 8 | - |
| JUN | Jun proto-oncogene | AP-1/AP1/c-Jun |
| LOX | Lysyl oxidase | MGC105112 |
| LTBP1 | Latent transforming growth factor beta binding protein 1 | MGC163161 |
| MMP1 | Matrix metallopeptidase 1 (interstitial collagenase) | CLG/CLGN |
| MMP13 | Matrix metallopeptidase 13 (collagenase 3) | CLG3/MANDP1 |
| MMP14 | Matrix metallopeptidase 14 (membrane-inserted) | 1/MMP-14/MMP-X1/MT-MMP/MT-MMP 1/MT1-MMP/MT1MMP/MTMMP1 |
| MMP2 | Matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | CLG4/CLG4A/MMP-II/MONA/TBE-1 |
| MMP3 | Matrix metallopeptidase 3 (stromelysin 1, progelatinase) | CHDS6/MGC126102/MGC126103/MGC126104/MMP-3/SL-1/STMY/STMY1/STR1 |
| MMP8 | Matrix metallopeptidase 8 (neutrophil collagenase) | CLG1/HNC/MMP-8/PMNL-CL |
| MMP9 | Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | CLG4B/GELB/MANDP2/MMP-9 |
| MYC | V-myc myelocytomatosis viral oncogene homolog (avian) | MRTL/bHLHe39/c-Myc |
| NFKB1 | Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | DKFZp686C01211/EBP-1/KBF1/MGC54151/NF-kappa-B/NF-kappaB/NFKB-p105/NFKB-p50/NFkappaB/p105/p50 |
| PDGFA | Platelet-derived growth factor alpha polypeptide | PDGF-A/PDGF1 |
| PDGFB | Platelet-derived growth factor beta polypeptide | FLJ12858/PDGF2/SIS/SSV/c-sis |
| PLAT | Plasminogen activator, tissue | DKFZp686I03148/T-PA/TPA |
| PLAU | Plasminogen activator, urokinase | ATF/UPA/URK/u-PA |
| PLG | Plasminogen | DKFZp779M0222 |
| SERPINA1 | Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | A1A/A1AT/AAT/MGC23330/MGC9222/PI/PI1/PRO2275/ alpha1AT |
| SERPINE1 | Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | PAI/PAI-1/PAI1/PLANH1 |
| SERPINH1 | Serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | AsTP3/CBP1/CBP2/HSP47/PPROM/RA-A47/SERPINH2/gp46 |
| SMAD2 | SMAD family member 2 | JV18/JV18-1/MADH2/MADR2/MGC22139/MGC34440/hMAD-2/hSMAD2 |
| SMAD3 | SMAD family member 3 | DKFZp586N0721/DKFZp686J10186/HSPC193/HsT174 36/JV15-2/MADH3/MGC60396 |
| SMAD4 | SMAD family member 4 | DPC4/JIP/MADH4 |
| SMAD6 | SMAD family member 6 | HsT17432/MADH6/MADH7 |
| SMAD7 | SMAD family member 7 | CRCS3/FLJ16482/MADH7/MADH8 |
| SNAI1 | Snail homolog 1 (Drosophila) | SLUGH2/SNA/SNAH/SNAIL/SNAIL1/dJ710H13.1 |
| SP1 | Sp1 transcription factor | - |
| STAT1 | Signal transducer and activator of transcription 1, 91kDa | DKFZp686B04100/ISGF-3/STAT91 |
| STAT6 | Signal transducer and activator of transcription 6, interleukin-4 induced | D12S1644/IL-4-STAT/STAT6B/STAT6C |
| TGFB1 | Transforming growth factor, beta 1 | CED/DPD1/LAP/TGFB/TGFbeta |
| TGFB2 | Transforming growth factor, beta 2 | MGC116892/TGF-beta2 |
| TGFB3 | Transforming growth factor, beta 3 | ARVD/FLJ16571/TGF-beta3 |
| TGFBR1 | Transforming growth factor, beta receptor 1 | AAT5/ACVRLK4/ALK-5/ALK5/LDS1A/LDS2A/SKR4/TGFR-1 |
| TGFBR2 | Transforming growth factor, beta receptor II (70/80kDa) | AAT3/FAA3/LDS1B/LDS2B/MFS2/RIIC/TAAD2/TGFR-2/TGFbeta-RII |
| TGIF1 | TGFB-induced factor homeobox 1 | HPE4/MGC39747/MGC5066/TGIF |
| THBS1 | Thrombospondin 1 | THBS/THBS-1/TSP/TSP-1/TSP1 |
| THBS2 | Thrombospondin 2 | TSP2 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | CLGI/EPA/EPO/FLJ90373/HCI/TIMP |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | CSC-21K |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | HSMRK222/K222/K222TA2/SFD |
| TIMP4 | TIMP metallopeptidase inhibitor 4 | - |
| TNF | Tumor necrosis factor | DIF/TNF-alpha/TNFA/TNFSF2 |
| VEGFA | Vascular endothelial growth factor A | MGC70609/MVCD1/VEGF/VPF |
| B2M | Beta-2-microglobulin | |
| HPRT1 | Hypoxanthine phosphoribosyltransferase 1 | HGPRT/HPRT |
| RPL13A | Ribosomal protein L13a | L13A/TSTA1 |
| GAPDH | Glyceraldehyde-3-phosphate dehydrogenase | G3PD/GAPD/MGC88685 |
| ACTB | Actin, beta | PS1TP5BP1 |
*
Shaded = Housekeeping genes