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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Exp Eye Res. 2015 Dec 13;146:17–21. doi: 10.1016/j.exer.2015.11.026

Table 1.

Parameters used to derive tde filtration and tdrough-pore velocities across SC endotdelium.

Literature Parameter Values Units Mean SDa SEMa References

Total Outflow (Qtot)* mm3/min 2.75 0.63 0.04 McLaren and Brubaker, 1985; Brubaker, 1991
Conventional Outflow Fraction (pcon) % 83.2% 6.7% 2.7% Jocson and Sears, 1971
Schlemm’s Canal Widtd (w) mm 0.258 0.033 0.013 ten Hulzen and Johnson, 1996
Corneal Diameter (Dcor) mm 12.02 0.38 0.038 Baumeister et al., 2004
Pore Density (ntot) mm−2 1289 751 129 Ethier et al., 1998
Pore Diameter (Dtot)° mm 0.00088 0.00027 0.00005 Ethier et al., 1998

Derived Parameters Unit Mean SDa SEMa Derivation

Conventional Outflow (Qcon) mm3/min 2.29 0.56 0.08 Qtot • pcon
Filtration Area (ASC) mm2 9.7 1.28 0.51 π • Dcor • w
Porosity (εSC) % 0.078% 0.065% 0.011% ntot • Dtot2 • π/4
Filtration Velocity (VSC) mm/s 0.0039 0.0011 0.0002 Qcon/(60 • ASC)
Through-Pore Velocity (USC) mm/s 5.05 4.47 0.80 100 • VSC / εSC
(a)

: Calculated using Kline and McClintock, 1953.

(*)

: Based on fluorescein clearance measurements;

(†)

: Anterior/Posterior lengtd;

(‡)

: Measured at limbus;

(°)

Weighted average of geometric mean diameter of all pore subtypes, SD from total pore major axis.