Table 1.
Crystallographic and structure refinement statistics*
| ΔL1 TEAD DBD | Se-Met ΔL1 TEAD DBD | |
|---|---|---|
| Data collection | ||
| Beamline | SSRL BL9-2 | ALS BL8.3.1 |
| Wavelenth (eV) | 12,658 | λ1=12,658 λ2=13,000 |
| Space group | C2221 | C2221 |
| Cell dimensions | ||
| a, b, c (Å) | 55.6, 96.5, 84.9 | 55.3, 95.7, 85.0 |
| α, β, γ (°) | 90, 90, 90 | 90, 90, 90 |
| Resolution (Å) | 48.27–2.09 (2.13–2.09) | 31.77–2.99 (3.16–2.99) |
| Rmerge | 0.058 (0.752) | 0.160 (0.760) |
| Rpim | 0.023 (0.291) | 0.068 (0.309) |
| Total # of observations | 101,091 (5151) | 32,491 (4729) |
| Total # unique | 13,625 (675) | 4,782 (679) |
| I/σI | 26.3 (3.1) | 9.5 (2.5) |
| Completeness (%) | 98.2 (96.0) | 9.5 (2.5) |
| Multiplicity | 7.4 (7.6) | 99.8 (99.4) |
| CC1/2 | 1.000 (0.907) | 0.93 (0.91) |
| Refinement | ||
| Resolution (Å) | 17.83–2.09 (2.26–2.09) | |
| Number of reflections | 13,598 (2,728) | |
| Rwork/Rfree | 0.237/0.253 | |
| Number of atoms | ||
| Protein | 1322 | |
| Water | 68 | |
| B-factors | ||
| Protein | 46.6 | |
| Water | 53.4 | |
| R.m.s. deviations | ||
| Bond lengths (Å) | 0.010 | |
| Bond angles (°) | 0.98 | |
| PDB ID | 4Z8E | |
*
Values in parentheses denote statistics for the highest resolution shell