Table 3.

Period Prevalence Rates of Internalizing and Externalizing Psychopathology and Associations with Initial AUD Onset during Late Adolescence

Predictor	Period Prevalence % [CI95]				Adjusted Associations with Time to AUD Onset during Late Adolescence HR [CI95]
	No AUD (n = 641)	AUD (n = 89)	Likelihood Ratio χ2	p-value
Early-To-Middle Adolescent Psychopathology
Internalizing domain	24.5 [21.6, 27.8]	27.9 [19.7, 37.8]	0.45	.490	1.32 [0.82, 2.12]
Mood disorders	21.1 [18.4, 24.1]	18.5 [12.2, 27.0]	0.34	.528	0.93 [0.54, 1.62]
Anxiety disorders	6.25 [4.8, 8.2]	8.58 [4.2, 16.9]	0.65	.433	1.53 [0.72, 3.22]
Bulimia nervosa	1.1 [0.6, 2.2]	0.8 [0.1, 5.3]	0.09	.723	0.81 [0.11, 6.23]
Externalizing domain	8.5 [6.7, 10.6]	17.9 [11.1, 27.7]	6.95	.010	2.05 [1.15, 3.67]
Disruptive behavior disorders	4.1 [2.9, 5.6]	4.7 [1.8, 11.3]	0.07	.784	0.91 [0.32, 2.59]
Other substance use disorders	5.1 [3.7, 6.8]	13.3 [7.4, 22.6]	7.53	.008	2.36 [1.19, 4.60]
Childhood Psychopathology
Internalizing domain	11.1 [9.1, 13.3]	7.8 [3.7, 15.5]	0.97	.322	0.85 [0.40, 1.80]
Mood disorders	6.2 [4.8, 8.1]	1.5 [0.4, 6.0]	4.40	.013	0.26 [0.06, 1.08]
Anxiety disorders	6.7 [5.2, 8.5]	7.0 [3.2, 14.6]	0.01	.907	1.58 [0.70, 3.55]
Bulimia nervosa	0.0	0.0	NA	NA	NA
Externalizing domain	3.5 [2.5, 4.9]	2.3 [0.7, 7.0]	0.38	.462	1.15 [0.35, 3.87]
Disruptive behavior disorders	3.0 [2.0, 4.3]	1.5 [0.4, 6.0]	0.69	.325	0.56 [0.13, 2.46]
Other substance use disorders	0.7 [0.3, 1.5]	0.8 [0.1, 5.3]	0.02	.885	1.45 [0.21, 9.91]

Note. Bolded table entries denote statistically significant effects.