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. 2016 Jun 5;129(11):1347–1354. doi: 10.4103/0366-6999.182833

Table 4.

Univariate Cox regression analyses of prognostic factors in Uyghur NPC patients

Factors 3-year OS 3-year DFS 3-year DMFS 3-year LRFS




HR (95% CI) P HR (95% CI) P HR (95% CI) P HR (95% CI) P
HLA-DRB1*0701 status 0.891 0.208 0.651 0.857
HLA-DRB1*0701 1 1 1 1
 Non-HLA-DRB1*0701 0.882 (0.146–5.311) 2.977 (0.544–16.289) 1.377 (0.344–5.510) 1.180 (0.196–7.117)
Gender 0.428 0.729 0.455 0.584
 Male 1 1 1 1
 Female 0.412 (0.046–3.697) 0.740 (0.135–4.065) 0.543 (0.109–2.699) 0.531 (0.055–5.123)
Age 0.361 0.242 0.233 0.290
 <45 years 1 1 1 1
 ≥45 years 2.316 (0.383–14.018) 2.614 (0.524–13.056) 2.332 (0.580–9.386) 2.637 (0.437–15.919)
Histological classification 0.332 0.292 0.162 0.333
 Differentiated type 1 1 1 1
 Nondifferentiated type 42.742 (0.022–84,224.802) 3.188 (0.369–27.580) 4.466 (0.547–36.430) 42.585 (0.021–85,148.450)
Clinical stage 0.676 0.674 0.617 0.579
 I + II 1 1 1 1
 III + IV 22.770 (0.000–5.362×107) 22.280 (0.000–4.170×107) 22.422 (0.000–4,337,407.866) 29.711 (0.000–4,810,491.419)
T-stage 0.535 0.943 0.492
 T1 + T2 1 1 1 0.847 1
 T3 + T4 26.478 (0.001–834,943.116) 0.925 (0.108–7.931) 1.229 (0.151–10.001) 29.732 (0.002–478,273.514)
N-stage 0.509 0.725 0.589 0.470
 N0 + N1 1 1 1 1
 N2 + N3 27.888 (0.001–538,949.647) 1.471 (0.171–12.629) 1.783 (0.219–14.541) 30.767 (0.003–332,472.900)

NPC: Nasopharyngeal carcinoma; HLA: Human leukocyte antigen; OS: Overall survival; DFS: Disease-free survival; DMFS: Distant metastasis-free survival; LRFS: Local relapse-free survival; HR: Hazard ratio; CI: Confidence interval.