Table 1.
demographic, clinical | ||||
---|---|---|---|---|
and cognitive measures | dlb ( n = 19) | ad ( n = 18) | hc ( n = 16) | p -value |
Male: female | 13:6 | 15:3 | 13:3 | Χ2 = 1.37, p = 0.504 |
Age; range | 76.32 ± 6.45; 62–89 | 75.39 ± 8.6; 62–88 | 76.75 ± 5.93; 62–84 | F2,50 = 0.16, p = 0.849† |
MMSE | 23.05 ± 4.13 | 21.83 ± 3.8 | 29.1 ± 0.88 | t35 = 0.93, p = 0.36* |
UPDRS | 14.95 ± 5.47 | 1.56 ± 1.68 | 1.44 ± 1.93 | t32 = 0.19, p = 0.85ⱡ |
CAMCOG | 74.26 ± 15.2 | 70.7 ± 14.5 | 96.8 ± 3.03 | t35 = 0.72, p = 0.47* |
CAF scale | 4.32 ± 4.43 | 0.65 ± 1.69b | na | t34 = 3.2, p = 0.003* |
NPI total | 5.39 ± 4.16a | 3.82 ± 4.12b | na | t33 = 1.11, p = 0.272* |
NPI hallucinations | 1.53 ± 1.77 | 0.0 ± 0.0b | na | t34 = 3.54, p = 0.001* |
Years since diagnosis | 1.0 ± 0.6 | 1.65 ± 0.8 | na | p-value = 0.013ⱡ |
AChEI (yes:no) | 18:1 | 18:0 | na | |
Levodopa (yes:no) | 8:11 | 0:18 | na |
Values expressed as mean ± 1SD.
a(n = 18).
b(n = 17).
†ANOVA DLB, AD, and HC.
*Student's t-test AD and DLB; ⱡStudent's t-test HC and AD, †two-tailed Mann–Whitney U test.
Abbreviations: DLB, dementia with Lewy bodies; AD, Alzheimer's disease; HC, Healthy controls; MMSE, Mini-Mental State examination; CAMCOG, Cambridge Cognitive Examination; NPI, Neuropsychiatric Inventory; CAF, Clinical Assessment of Fluctuating Confusion; VP, Visual Perception; UPDRS, Unified Parkinson's Disease Rating Scale; AChEI, patients on AChEI treatment; Levodopa, patients on Levodopa; na, not applicable.