FIG. 2.
SAHA attenuates p38 activation for up to 48 h. The cytosol fraction from the livers of mice treated with SAHA at 3, 24, and 48 h after LPS insult was subjected to western blot with anti-phospho-p38 and p38 antibodies. Upper panel shows a representative western blot. The levels of phospho-p38 remained low in the SAHA treated group even 48 h after LPS and SAHA injection. There was no significant difference between phospho-p38 expression at 3, 24, or 48 h. Bars represent standard error (SE).
