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. Author manuscript; available in PMC: 2017 May 27.
Published in final edited form as: Annu Rev Phys Chem. 2016 May 27;67:691–717. doi: 10.1146/annurev-physchem-031215-010949

Figure 7.

Figure 7

Enhanced fluorescence detection sensitivity demonstrated in a single-component bioassay. DNA hybridization reactions were performed on a stripe-patterned ZnO NR platform. Strong fluorescence emission was observed from a sample containing a fully complementary pair of single-stranded DNA fragments in chamber 2, whereas no signal was detected from noncomplementary strands in chamber 1. DNA duplex formation assays were also performed as a function of target DNA concentration to determine detection sensitivity. Data shown in red and blue were obtained from the hybridization assays employing a covalent and noncovalent linking scheme of probe DNA strands on ZnO NRs, respectively. Abbreviations: NR, nanorod; PDMS, polydimethylsiloxane. Figure adapted from Reference 50 with permission. Copyright 2006 Institute of Physics Publishing.