Table 1. IPA analysis of significant genes and pathways up-regulated in GBM+&AD− and GBM−&AD+ gene sets.
| GBM+&AD− | ||
|---|---|---|
| Significant Pathways | P-Value | Ratio |
| cAMP-mediated signaling | 4.07E-05 | 5.16E-02 |
| IL-3 Signaling | 1.86E-04 | 8.22E-02 |
| 14-3-3-mediated Signaling | 3.80E-04 | 6.09E-02 |
| Axonal Guidance Signaling | 7.08E-04 | 3.08E-02 |
| Rac Signaling | 1.38E-03 | 5.13E-02 |
| Protein Kinase A Signaling | 2.82E-03 | 3.27E-02 |
| Inositol Phosphate Metabolism | 4.90E-03 | 4.44E-02 |
| IGF-1 Signaling | 5.75E-03 | 4.90E-02 |
| ERK/MAPK Signaling | 6.17E-03 | 3.54E-02 |
| Inhibition of Angiogenesis by TSP1 | 6.76E-03 | 9.09E-02 |
| Glutamate Metabolism | 7.94E-03 | 8.57E-02 |
| Chemokine Signaling | 8.91E-03 | 5.80E-02 |