Figure 1. Dynamic light scattering (DLS) size distributions for Ln–SPIO nanoparticles.

(A) Size comparison of the four nanoparticle formulations prior to conjugation to targeting ligands. (B) Representative TEM images of the four nanoparticle formulations. (C) Dynamic light scattering profiles of each nanoparticle formulation after conjugation to its respective targeting ligand. The size profile was also examined in a sample where all formulations were combined into a single sample (mixed).