Table 4. Association of POMS factors with SNPs*.
Placebo (0 mg) | Nicotine Gum (2 mg) | Nicotine Gum (4 mg) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP | Beta | Se | Z | P | Beta | Se | Z | P | Beta | Se | Z | P |
Friendly | ||||||||||||
rs16969968 | 0.065 | 0.110 | 0.593 | 0.5530 | 0.071 | 0.108 | 0.655 | 0.5120 | 0.065 | 0.114 | 0.569 | 0.5690 |
rs578776 | 0.126 | 0.110 | 1.146 | 0.2520 | 0.181 | 0.109 | 1.671 | 0.0950 | 0.155 | 0.111 | 1.397 | 0.1620 |
rs588765 | −0.023 | 0.102 | −0.22 | 0.8230 | −0.038 | 0.100 | −0.375 | 0.7080 | −0.039 | 0.103 | −0.380 | 0.7040 |
Active | ||||||||||||
rs16969968 | 0.189 | 0.110 | 1.720 | 0.0850 | 0.261 | 0.110 | 2.378 | 0.0170 | 0.228 | 0.115 | 1.977 | 0.0480 |
rs578776 | 0.095 | 0.110 | 0.866 | 0.3870 | 0.205 | 0.110 | 1.856 | 0.0630 | 0.155 | 0.118 | 1.320 | 0.1870 |
rs588765 | 0.011 | 0.102 | 0.110 | 0.9130 | 0.031 | 0.100 | 0.308 | 0.7580 | 0.049 | 0.105 | 0.466 | 0.6420 |
Clear Headed | ||||||||||||
rs16969968 | −0.106 | 0.125 | −0.85 | 0.3970 | −0.061 | 0.130 | −0.472 | 0.6370 | 0.002 | 0.126 | 0.019 | 0.9850 |
rs578776 | 0.082 | 0.130 | 0.636 | 0.5250 | 0.083 | 0.115 | 0.721 | 0.4710 | 0.115 | 0.127 | 0.907 | 0.3640 |
rs588765 | −0.111 | 0.116 | −0.957 | 0.3390 | −0.041 | 0.116 | −0.348 | 0.7270 | 0.004 | 0.121 | 0.031 | 0.9750 |
Uneasy | ||||||||||||
rs16969968 | 0.164 | 0.134 | 1.220 | 0.2220 | 0.166 | 0.123 | 1.349 | 0.1770 | 0.132 | 0.120 | 1.099 | 0.2720 |
rs578776 | −0.188 | 0.138 | −1.366 | 0.1720 | −0.017 | 0.126 | −0.134 | 0.8930 | −0.218 | 0.119 | −1.830 | 0.0670 |
rs588765 | 0.236 | 0.129 | 1.822 | 0.0690 | 0.109 | 0.126 | 0.861 | 0.3890 | 0.243 | 0.121 | 2.013 | 0.0440 |
Fatigued | ||||||||||||
rs16969968 | 0.132 | 0.128 | 1.032 | 0.3020 | −0.013 | 0.124 | −0.107 | 0.9150 | −0.045 | 0.123 | −0.368 | 0.7130 |
rs578776 | 0.090 | 0.121 | 0.750 | 0.4530 | −0.065 | 0.126 | −0.517 | 0.6050 | −0.109 | 0.126 | −0.865 | 0.3870 |
rs588765 | 0.056 | 0.114 | 0.491 | 0.6230 | 0.048 | 0.120 | 0.398 | 0.6900 | 0.037 | 0.115 | 0.321 | 0.7480 |
*P values ≤ 0.05 were highlighted by bold fonts, and p values ≤ 0.1 were highlighted by italic fonts and underscored.