Table 2. Effects of intracellular NA on heat-sensing TRPV channels.
INA/I2-APB | I(NA + 2-APB)/I2-APB | |
---|---|---|
TRPV1 | 135 ± 5% *** (n = 4) | 120.1 ± 2.3% *** (n = 11) |
TRPV2 | - | 19.0 ± 8.5% *** (n = 6)# |
TRPV3 | 0.6 ± 0.1% (n = 5) | 181.2 ± 28.4% *** (n = 5)§ |
TRPV4_dm | 19.2 ± 0.1% *** (n = 4) | N.D. |
[NA] = 65 mM, [2-APB] = 1 mM.
#130 mM NA and 4 mM 2-APB were used for this test.
§130 mM NA was used for this test.
***p < 0.005.