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. Author manuscript; available in PMC: 2016 Jun 6.
Published in final edited form as: Nat Struct Mol Biol. 2011 Nov 27;18(12):1331–1335. doi: 10.1038/nsmb.2189

Fig. 3.

Fig. 3

Atr suppresses Myc-induced RS and apoptosis. (a) Images illustrating the staining pattern of the γH2ax (red) signal on MycER infected MEF. Scale bar indicates 10 μm. (b) Percentage of cells showing a pan-nuclear distribution of γH2ax in MycER infected MEF of the different genotypes in the presence or absence of 4-OHT for 24 hrs. (c) Cell cycle profiles of MycER infected MEF of the different genotypes in the presence or absence of 4-OHT for 24 or 48 hrs. Sub-G1 (red) and S+G2 (blue) percentages are indicated. The images show a representative experiment that was repeated 3 times with independent MEF pairs. (**: P<0.01; ***: P<0.001)