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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Neuropharmacology. 2016 Jan 9;105:639–650. doi: 10.1016/j.neuropharm.2016.01.004

Figure 4.

Figure 4

Gene expression of three opioids peptides, proopiomelanocortin (Pomc, A), prodynorphin (Pdyn, B), proenkephalin (Penk, C), and three opioid receptors, mu (Oprm, D), kappa (Oprk, E), and delta (Oprd, F), in the nucleus accumbens shell of Fischer and Lewis rats sacrificed 24 h after the last 18-h operant session (cocaine). Control rats underwent same self-administration procedure, but with saline in place of cocaine (yoked-saline). Panels represent Mean±SEM expressed as the percent of Fischer yoked-saline. # p< 0.05 versus Fischer yoked-saline (SNK post-hoc test).