Silverman 2001.
Methods | RCT. Groups similar in terms of demographic and baseline drug use. | |
Participants | 40 pregnant, unemployed, women 18 to 50 years old on MMT, and with positive urine toxicology for opiates within 6 weeks prior to enrolment. Mean age 32; 83% African America; 65% HS or greater education; 7.5% married; 100% unemployed; 100% used cocaine; 75% used cocaine. Exclusion: at risk for suicide, psychiatric disorder. | |
Interventions | For all participants, substance abuse counselling and MMT provided. Details of counselling not given. No mention of MMT doses or schedule.
Duration 24 weeks. |
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Outcomes | Retention in treatment defined as remaining in the study through 24 weeks and reported as N and %. Urine toxicology reported as % negative over total study period for each group, and reported as overall positive and drug‐specific positive. Attendance in Therapeutic Workplace was calculated and presented in a bar graph for each woman. | |
Notes | Transportation and childcare provided at no cost. We attempted to contact trial authors but received no answer. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | "A modified dynamic balanced randomization was used to randomize patients sequentially to the treatment conditions." |
Allocation concealment (selection bias) | Unclear risk | Allocation concealment was not described. |
Incomplete outcome data (attrition bias) All outcomes | Low risk | Attrition details outlined, reasons for leaving also outlined. Different methods utilized to attempt to account for missing data. |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | No references to outcome assessor blinding made. |