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. Author manuscript; available in PMC: 2016 Sep 7.
Published in final edited form as: Nat Methods. 2016 Mar 7;13(4):345–351. doi: 10.1038/nmeth.3801

Figure 1. Saposin-lipoprotein nanoparticles for the incorporation of lipids, membrane proteins and viral antigens.

Figure 1

By incubating Saposin A with lipids and membrane proteins it is possible to generate soluble and stable nanoparticles that adjust to the size of the incorporated molecule. Models of Saposin-Lipid-complexes were adapted from pdbs: 4ddj, 4aps, 4nco, 3din, 2dob; virus envelope structure modified49