Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jun 6;12(6):e1006057. doi: 10.1371/journal.pgen.1006057

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Meier et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Fig 1 — Schematic domain architecture of human Drosha and Dicer, DCL1 from A. thaliana (A.th.) and DrnA and DrnB from D. discoideum (D.d.) is shown. DsRBD (double stranded RNA binding domain), RIII (Ribonuclease III domain), HELICc (helicase superfamily c-terminal domain), DEXDc (Dead-like Helicases superfamily domain), PAZ (PAZ-domain), DUF283 (DUF283 domain). Human Drosha contains a region that is rich in prolines (P-rich site) as well as a region that is rich in serine and arginine (S/R-rich). DrnA and DrnB lack the Helicase domains, the DUF283 domain as well as the PAZ domain. DrnB exhibits a proline and serine rich (P/S-rich) region. Proteins and Domains are drawn to scale.