Table 2.
Participant Characteristics
| Demographics and Health Information | N | Visit 1 | N | Visit 2 |
|---|---|---|---|---|
| Women N (%) | 150 | 82 (54.7) | - | - |
| Baseline Age (years) | 150 | 67.2 (6.7) | 150 | 77.7 (6.7) |
| White N (%) | 150 | 98 (65.3) | - | - |
| Time between blood and DTI (years) | 150 | 10.5 (1.6) | - | - |
| Body Mass Index (kg/m) | 150 | 27.3 (4.2) | 135 | 26.8 (4.2) |
| Diabetes N (%) | 150 | 9 (6.0) | 135 | 11(8.1) |
| Hypertension N (%) | 150 | 58 (38.7) | 135 | 53 (39.3) |
| Systolic BP (mmHg) | 134 | 134.4 (19.5) | 135 | 115.8 (14.5) |
| Diastolic BP (mmHg) | 134 | 77.9 (10.8) | 135 | 62.3 (9.1) |
| APOE E4 Carrier N (%) | 150 | 38 (25.3) | - | - |
| Total cholesterol (mg/dl) | 145 | 199.2 (34.8) | 134 | 183.7 (36.1) |
| Triglycerides (mg/dl) | 142 | 109.1 (66.0) | 133 | 95.7 (44.9) |
| Statin use N (%) | 150 | 30 (20.0) | 135 | 49 (36.3) |
| Cancer N (%) | 150 | 18 (12.0) | 135 | 25 (18.5) |
| Myocardial infarction N (%) | 150 | 3 (2.0) | 135 | 6 (4.4) |
| Education (years) | 150 | 16.6 (2.5) | - | - |
| MMSE | 124 | 29.0 (1.2) | 133 | 28.6 (1.5) |
Mean and standard deviation unless otherwise noted. Visit 1 information is concurrent with the visit at which the sphingolipids were assayed, and visit 2 is concurrent with DTI. APOE E4 = apolipoprotein E4. BP = blood pressure. MMSE = Mini-mental state examination.