Table 3.
Characteristics of patients included in incidence of subsequent colorectal neoplasia (CRN) analysis
| History of prior or synchronous CRN | ||||||
|---|---|---|---|---|---|---|
| Without | With | |||||
| SEC | Control | P-value | SEC | Control | P-value | |
| N | 36 | 76 | – | 17 | 24 | – |
| Median age years (IQR) | 58 (49–64) | 54 (51–58) | 0.2 | 59 (51–69) | 60 (55–62) | 0.9 |
| Males (%) | 22 (61%) | 40 (53%) | 0.4 | 11 (65%) | 10 (42%) | 0.2 |
| CUC (%) | 31 (86%) | 57 (75%) | 0.2 | 15 (88%) | 18 (75%) | 0.4 |
| Median IBD duration at index, years (IQR) | 19 (14–30) | 20.5 (11–29) | 0.7 | 14 (10–26) | 17.5 (9–22) | 0.7 |
| Extensive disease (%) | 30 (83%) | 63 (83%) | 1.0 | 12 (71%) | 21 (88%) | 0.2 |
| Colectomy (%) | 2 (6%) | 4 (5%) | 1.0 | 3 (18%) | 1 (4%) | 0.3 |
| PSC (%) | 11 (31%) | 16 (21%) | 0.3 | 4 (24%) | 3 (13%) | 0.4 |
| Smoking (%) | ||||||
| Current | 3 (8%) | 4 (5%) | 0.7 | 1 (6%) | 1 (4%) | 1.0 |
| Past | 12 (33%) | 17 (22%) | 0.3 | 5 (29%) | 12 (50%) | 0.2 |
| Never | 21 (58%) | 53 (70%) | 0.3 | 10 (59%) | 11 (46%) | 0.5 |
| Unknown | 0 (0%) | 2 (3%) | 0.6 | 1 (6%) | 0 (0%) | 0.4 |
| Median follow-up, months (IQR) | 31 (19–57) | 29 (14–37) | 0.2 | 20 (12–29) | 32 (7–37) | 0.07 |
SEC, serrated epithelial change; IQR, interquartile range; CUC, chronic ulcerative colitis; IBD, inflammatory bowel disease; PSC, primary sclerosing cholangitis.