Table 3.
Cardiac data
| Baseline | 12 h | 24 h | |
|---|---|---|---|
| LVESP (mmHg) | |||
| Sham | 102 (92; 117) | 99 (91; 114) | 112 (87; 123) |
| Sepsis | 105 (86; 114) | 100 (89; 110) | 90; 67; 101)* |
| LVEDP (mmHg) | |||
| Sham | 14 (9; 19) | 14 (9; 20) | 18 (13; 23) |
| Sepsis | 11 (9; 17) | 17 (14; 20) | 18 (14; 21) |
| dp/dtmax (mmHg/s) | |||
| Sham | 1797 (1675; 2170) | 2573 (1412; 4028) | 2224 (1857; 3590) |
| Sepsis | 1571 (1341; 2025) | 4239 (1817; 4608)* | 3150 (1794; 5122)* |
| dp/dtmin (mmHg/s) | |||
| Sham | −2222 (−2473; −1904) | −2148 (−2423; −1293) | −2461 (−2748; −1246) |
| Sepsis | −1971 (−2257; −1735) | −2090 (−2436; −1743) | −2180 (−2719; −1556) |
| SV (ml) | |||
| Sham | 50 (46; 59) | 47 (45; 59) | 47 (43; 54) |
| Sepsis | 44 (39; 67) | 49 (39; 67) | 42 (31; 66) |
| EF (%) | |||
| Sham | 45 (44; 49) | 49 (44; 66) | 39 (34; 49) |
| Sepsis | 50 (41; 61) | 49 (34; 58) | 60 (40; 78) |
| LVESV (ml) | |||
| Sham | 59 (52; 65) | 49 (24; 75) | 75 (46; 104) |
| Sepsis | 37 (30; 80) | 53 (41; 109) | 31 (24; 44) |
| LVEDV (ml) | |||
| Sham | 116 (102; 129) | 105 (78; 137) | 131 (97; 168) |
| Sepsis | 94 (78; 118) | 99 (90; 204) | 86 (62; 114) |
| Tau (ms) | |||
| Sham | 28 (26; 35) | 27 (25; 41) | 26 (23; 45) |
| Sepsis | 28 (25; 38) | 21 (19; 26) | 18 (14; 23)*,** |
All data are medians (25; 75 percentile). Sham n = 5; sepsis n = 8
LVESP left ventricular end-systolic pressure, LVEDP left ventricular end-diastolic pressure, dp/dt max maximal rate of pressure increase, dp/dt min maximal rate of pressure decrease, SV stroke volume, EF ejection fraction, LVESV left ventricular end-systolic volume, LVEDV left ventricular end-diastolic volume
* p < 0.05 compared to baseline; ** p < 0.05 compared to sham group