Table 1.
Demographic and clinical characteristics of studied groups
| Variables | CAD+ (n = 107) | CAD− (n = 202) | p value |
|---|---|---|---|
| Age (years) | 69.61 ± 10.51 | 61.20 ± 14.83 | <.001 |
| Sex (M/F) | 64/43 | 93/109 | <.001 |
| Dialysis duration (years) | 6.01 ± 6.16 | 6.52 ± 6.40 | >.050 |
| BMI (kg/m2) | 27.47 ± 5.62 | 24.87 ± 4.93 | <.001 |
| Albumin (g/dl) | 3.86 ± .36 | 3.98 ± .39 | <.050 |
| Hemoglobin (g/dl) | 10.6 ± 1.3 | 11.00 ± 1.45 | <.050 |
| EPO demand (IU)/week | 3841.58 ± 2704.04 | 3568.42 ± 2793.81 | >.050 |
| Diabetes mellitus (%) | 48 (44.9) | 41 (20.4) | <.050 |
| Stroke in anamnesis (%) | 13 (12.1) | 12 (6.0) | >.050 |
| Hyperlipidemia (%) | 65 (61.3) | 87 (43.5) | <.010 |
| Family history of CVD | 21 (19.6) | 21 (10.4) | <.010 |
| Smoking | 21 (19.6) | 27 (13.4) | >.050 |
| Alcoholism | 2 (1.9) | 6 (3) | >.050 |
| Rs10887800 | |||
| GG/AG/AA | 32/51/24 | 39/110/53 | .108 |
| GG versus (AG + AA) | 32/75 | 39/163 | .035 |
| G versus A | .54/.46 | .47/.53 | .088 |
| Rs2576178 | |||
| GG/AG/AA | 10/43/54 | 13/75/114 | .490 |
| G versus A | .29/.71 | .25/.75 | .251 |
Continuous variables are presented as mean ± SD. Discrete variables are presented as numbers and percentages (in parentheses)
EPO erythropoietin, CVD cardiovascular disorder, CAD coronary artery disease