Tab. 2.
Predictors of appropriate implantable cardioverter-defibrillator therapy in primary preventative therapy of tetralogy of Fallot (0–2 points is low risk, 3–5 points intermediate risk and 6–12 points high risk. Adapted from Khairy et al. [20]). Significant factors on univariate and multivariate analysis are highlighted in italics
HR | 95 % CI | Univariate analysis | Multivariate analysis | Points attributed | |
---|---|---|---|---|---|
Prior palliative shunt | 2.6 | 0.7–9.4 | 0.13 | 2 | |
Inducible sustained VT | 2.1 | 0.6–7.6 | 0.24 | 2 | |
QRS duration, per 1 ms | 1.01 | 0.99–1.03 | 0.21 | ||
QRS ≥ 180 ms | 2.0 | 0.7–5.9 | 0.22 | 1 | |
Ventriculotomy incision | 2.4 | 0.9–6.1 | 0.071 | 2 | |
Nonsustained VT | 2.7 | 1.0–7.2 | 0.053 | 0.023 | 2 |
RV systolic pressure, per 1 mmHg | 1.06 | 1.01–1.11 | 0.0301 | ||
Mean PAP, per 1 mmHg | 1.16 | 1.05–1.35 | 0.0032 | ||
LVEDP, per 1 mmHg | 1.21 | 1.08–1.35 | 0.0008 | 0.0039 | |
LVEDP ≥ 12 mmHg | 15.1 | 1.9–123.7 | 0.0114 | 0.022 | 3 |
HR hazard ratio, CI confidence interval, VT ventricular tachycardia, PAP pulmonary artery pressure, LVEDP left ventricular end diastolic pressure, RV right ventricle