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. 2016 May 24;2016:6462120. doi: 10.1155/2016/6462120

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Copyright © 2016 Maria Elizabeth Pereira Nobre et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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ω3 treatments of ischemic animals (3 animals per group) drastically decreased the neuronal degeneration (visualized by an intense fluorescence to Fluoro-Jade) in hippocampus and cortex. The effects in CA1 and CA3 and DG are represented by photomicrographs and quantitative measurements performed with the Image J software, from 3 to 6 fields. The groups are sham-operated (SO); ischemic (ISC) untreated, and ischemic after ω3 treatments (5 mg/kg, for 7 days). CA1: (A) versus SO, q = 10.98^∗∗∗; (B) versus ISC + ω3, q = 10.34^∗∗∗. CA3: (A) versus SO, q = 14.57^∗∗∗; (B) versus ISC + ω3, q = 20.55^∗∗∗; (C) versus SO, q = 5.979^∗∗ (one-way ANOVA and Newman-Keuls test as the post hoc test).