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. 2016 Jun 7;3(3):ENEURO.0094-16.2016. doi: 10.1523/ENEURO.0094-16.2016

Figure 7.

Figure 7.

Estradiol but not progesterone increases overall excitability and burst events in AVPV kisspeptin neurons. A, Representative extracellular recordings of OVX, OVX+E, OVX+E+P, and OVX+E+V with AMPA, NMDA, and GABAA receptors antagonized. Gray boxes indicate bursts. B, C, Mean ± SEM firing frequency (B) and number of burst events (C) of OVX (black circles), OVX+E (solid red circles), OVX+E+V (open red circles), and OVX+E+P (blue). D, Percentage of cells that fire DIB or tonic patterns on OVX, OVX+E, and OVX+E+P groups. E, Representative firing properties of tonic (top) and DIB (bottom; except OVX) cells in OVX, OVX+E, and OVX+E+P groups. F–H, Mean ± SEM of action potential parameters in OVX (white), OVX+E (hatched), and OVX+E+P (black) groups: latency to first spike (F), action potential FWHM (G), and AHP potential (amplitude; H). *p < 0.05 calculated by one-way ANOVA/Bonferroni test or Kruskal–Wallis or Dunn’s test, as dictated by data distribution.