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. 2016 Jun 7;6:27192. doi: 10.1038/srep27192

Figure 6. Immunohistochemical study for ERK and MAC2.

Figure 6

(a) ERK phosphorylation was increased in a glomerulus, including mesangial cells and podocytes, of db/db Cav2.2+/+ mice. Its increase was ameliorated in a glomerulus of db/db Cav2.2−/− mice. (b,c) Mac-2-positive cells in glomeruli increased in db/db Cav2.2+/+ mice compared with those in db/+ Cav 2.2+/+ mice and suppressed in db/db Cav2.2−/− mice. **p < 0.01. Scale bar = 50 μm.