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. 2016 Jan 11;17(Suppl 1):5. doi: 10.1186/s12859-015-0847-y

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© Lyu and Li. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Calibration and comparison of discriminative power in the simulation with violation of model assumption. a. The estimated error rate is compared with the empirical FDR for the simulation setting S1. Results from other simulation settings are similar (Additional file 1: Figure S1). b. The percentage of correct and incorrect calls at various thresholds for our method, Fisher’s method, Stouffer’s method and RankProd, for the simulation setting S1. Results from other simulation settings are similar (Additional file 1: Figure S2)