Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jun 7;6:27479. doi: 10.1038/srep27479

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A) The Breg levels among DM patients (n = 30), diseased controls (DC) (n = 37), and healthy controls (HC) (n = 23). The results were expressed by scatter dots plot depicting mean ± SEM. A significant decrease was observed in the frequency of CD19⁺ CD24^highCD38^high Bregs in DM patients compared to those in healthy controls (0.713 ± 0.275% vs 4.196 ± 0.347%, p < 0.0001) and in diseased controls (0.713 ± 0.275% vs 4.010 ± 0.566%, p < 0.0001) (A, left). The absolute number of Bregs was also significantly lower in DM patients than in healthy controls (1.079 ± 0.358 × 10⁶ vs 4.267 ± 0.301 × 10⁶, p < 0.0001) and diseased controls (1.079 ± 0.358 × 10⁶ vs 3.981 ± 0.551 × 10⁶, p < 0.0001) (A, right). (B) Representative cases of a healthy control (B, left) and of a DM patient (B, right).